Meningeal Dissemination of Retinoblastoma: CT Findings

نویسندگان

  • Francisco J. Meli
  • Carlos A. Boccaleri
  • Julio Manzitti
  • Pedro Lylyk
  • Juan P. Garrahan
چکیده

Thirty-seven patients with retinoblastoma were evaluated prospectively by clinical examination, lumbar puncture, and CT. Eight (22%) of the 37 were found to have meningeal dissemination. The tumor was bilateral in three patients. Two cases showed no CT signs of local recurrence. Headache, nauseajvomiting, and restlessness were the most common symptoms. CT scans in these patients showed diffuse meningeal contrast enhancement, nodular masses, ependymal-subependymal enhancement, and ventricular dilatation. Our series of eight patients with meningeal spread illustrates a considerable range of dissemination patterns referable to retinoblastoma. One case illustrated the CT finding of multiple epidural metastases.

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تاریخ انتشار 2013